Case Study 2
Maria is a sedentary, 68-year-old woman who is overweight. She
complains that her hands and feet are always cold, and she tires quickly when
cleaning the house. At her most recent visit to her doctor, her blood pressure
was 184/98 mm Hg. She has edema around her ankles and legs, and her physician
is concerned about an echocardiogram that indicates Maria has an enlarged
1.  Identify two
reasons why Maria will have tissue ischemia. How might this lead to hypoxia?
2.  What two early
and reversible changes occur to tissue cells when they are hypoxic?
3.   What specific type of cellular adaptation has
taken place in Maria’s enlarged heart? What made you come to this conclusion?
4. Predict why Maria’s heart has become enlarged.
Why doesn’t this enlargement give her the same cardiac strength and endurance
as a well-trained athlete?
Assignment Requirements:
finalizing your work, you should:
Ensure you have written at least four double-spaced pages.
be sure to read the Assignment description carefully (as
displayed above);
consult the Grading Rubric (under the Course Home) to make
sure you have included everything necessary; and
utilize spelling and grammar check to minimize errors.
follow the conventions of Standard American English (correct
grammar, punctuation, etc.);
be well ordered, logical, and unified, as well as original
and insightful;
display superior content, organization, style, and mechanics;
use APA 6th Edition format as outlined in the APA Progression

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