Case Study 1
Mechanisms of Infectious
Thirty-two–year-old Jason is
a general laborer, who fell ill shortly after working on a job digging up old
water pipes for the town he lived in. The task involved working around shallow
pools of stagnant water. Ten days after the contract ended, Jason developed a
fever and aching muscles. He also had nausea, vomiting, and diarrhea. Jason’s
friend took him to his physician who listened carefully to Jason’s history. She
told him she suspected West Nile fever and ordered serological testing. Jason
went home to recover and was feeling better by the end of the week.

Jason’s physician ordered serological tests. How would
antibody titers assist the doctor in confirming his diagnosis?
When Jason was feeling at his worst, he had extreme
malaise, vomiting, and diarrhea. What stage of the illness was he
experiencing at that time? What are the physiological mechanisms that give
rise to the signs and symptoms of infectious illness?
West Nile virus has a single-stranded RNA genome. How
does this virus replicate? In general terms, what are the various effects
viruses can have on host cells?

Assignment Requirements:
finalizing your work, you should:
Ensure you have written at least four double-spaced pages.
be sure to read the Assignment description carefully (as
displayed above);
consult the Grading Rubric (under the Course Home) to make
sure you have included everything necessary; and
utilize spelling and grammar check to minimize errors.
follow the conventions of Standard American English (correct
grammar, punctuation, etc.);
be well ordered, logical, and unified, as well as original
and insightful;
display superior content, organization, style, and mechanics;
use APA 6th Edition format as outlined in the APA Progression

Make sure all of the topics in the case study have been
Cite at least three sources—journal articles,
textbooks, or evidenced-based websites—to support the content.
All sources must have been written within five years.
Do not use .com, Wikipedia, or up-to-date, etc., for
your sources.

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